Causal association between particulate matter 2.5 and Alzheimer’s disease: a Mendelian randomization study

• DOI: 10.3389/fpubh.2024.1343915
• Publication Date: 2024-05-30T08:57:00Z
• Authors: Meijuan Dang; Ye Li; Lili Zhao; Tao Li; Ziwei Lu; Jialiang Lu; Yuxuan Feng; Yang Yang; Fangcun Li; Fan Tang; Xiaoya Wang; Yating Jian; Heying Wang; Lei Zhang; Hong Fan; Guilian Zhang
• Keywords: Mendelian Randomization

Although epidemiological evidence implies a link between exposure to particulate matter (PM) and Alzheimer's disease (AD), establishing causality remains complex endeavor. In the present study, we used Mendelian randomization (MR) as robust analytical approach explore potential causal relationship PM AD risk. We also explored associations other neurodegenerative diseases.