Impact of Diffuse Idiopathic Skeletal Hyperostosis on Clinico-Radiological Profiles and Prognosis for Thoracic Ossification of Ligamentum Flavum-Myelopathy: A Propensity-Matched Monocentric Analysis

• DOI: 10.3390/diagnostics12071652
• Publication Date: 2022-07-07T11:51:56Z
• Authors: Baoliang Zhang; Guanghui Chen; Xi Chen; Zhongqiang Chen; Chuiguo Sun
• Keywords: Hyperostosis; Thoracic spine

Background: Diffuse idiopathic skeletal hyperostosis (DISH) has been evaluated as a potential risk factor of poor surgical outcomes for lumbar spinal stenosis, whereas the influence DISH on neuroimaging characteristics and postoperative prognosis patients with thoracic myelopathy not established. Therefore, this study aimed to shed light issue. Methods: A monocentric enrolled 167 eligible ossification ligamentum flavum (TOLF), who were followed up at least 2 years. Clinico-radiological parameters compared between DISH+ DISH− groups before after propensity matching. Subgroup analysis was conducted compare functional mild (M-DISH) moderately severe (MS-DISH) groups. Results: Fifty-eight diagnosed DISH, its prevalence 34.7%. Patients presented older age, more males, taller stature, heavier weight, commonly diffuse-type TOLF (p < 0.05). The group showed significantly worse recovery rate (RR) final follow-up matching 0.01), slightly lower preoperative VAS, higher VAS reduction, despite reaching significant differences. demonstrated that M-DISH associated mJOA score = 0.01) RR 0.001), tended present than MS-DISH group. Conclusions: predisposition elderly males TOLF. Although presence might bring about suboptimal outcome, both non-DISH experienced good neurological function improvements pain relief through posterior decompression.