Non-mass Breast Lesions: Could Multimodal Ultrasound Imaging Be Helpful for Their Diagnosis?

• DOI: 10.3390/diagnostics12122923
• Publication Date: 2022-11-24T07:25:36Z
• Authors: Wenjuan Guo; Tong Wang; Fan Li; Chao Jia; Siqi Zheng; Xuemei Zhang; Min Bai
• Keywords: Breast imaging; Breast ultrasound; Ultrasound imaging

Objective: To develop a prediction model for discriminating malignant from benign breast non-mass-like lesions (NMLs) using conventional ultrasound (US), strain elastography (SE) of US and contrast-enhanced (CEUS). Methods: A total 101 NMLs 100 patients detected by were enrolled in this retrospective study. The characteristics US, SE CEUS compared between NMLs. Histopathological results used as the reference standard. Binary logistic regression analysis was performed to identify independent risk factors. multimodal method evaluate based on developed. diagnostic performance + SE, combination these modalities evaluated compared. Results: Among lesions, 50 (49.5%) 51 (50.5%) malignant. Age ≥45 y, microcalcifications lesion, elasticity score >3, earlier enhancement time hyper-enhancement indicators included establish method. area under receiver operating characteristic curve (AUC) significantly higher than that (p < 0.0001) 0.0001), but there no significant difference AUC = 0.216). Conclusion: could improve efficiency accuracy diagnosis