Analysis of OCT Scanning Parameters in AMD and RVO

• DOI: 10.3390/diagnostics14050516
• Publication Date: 2024-02-29T10:59:19Z
• Authors: Claus von der Bur...; Johann Roider; Timo Kepp
• Keywords: Imaging biomarker

Optical coherence tomography (OCT) is an extensively used imaging tool for disease monitoring in both age-related macular degeneration (AMD) and retinal vein occlusion (RVO). However, there limited literature on minimum requirements of OCT settings reliable biomarker detection. This study systematically investigates the influence scan size interscan distance (ISD) activity We analyzed 80 volumes AMD patients 12 RVO presence subretinal fluid (SRF), intraretinal (IRF), pigment epithelium detachment (PED). All volume scans had a 6 × mm ISD 125 µm. general distribution how detection sensitivity decreases when reducing or density. found that patients, all fluids were nearly normally distributed, with most occurrences foveal center concentric decrease towards periphery. When to 3 2 mm, was still high (0.98 0.96). Increasing only slightly can already compromise (0.9 250 µm against ISD).