Incidence Density and Risk Factors of Diabetic Retinopathy Within Type 2 Diabetes: A Five-Year Cohort Study in China (Report 1)

• DOI: 10.3390/ijerph120707899
• Publication Date: 2015-07-13T07:49:22Z
• Authors: Lei Liu; Jingyang Wu; Song Yue; Jin Geng; Jie Lian; Weiping Teng; Desheng Huang; Lei Chen
• Keywords: Male; China; Article; Cohort Studies; 03 medical and health sciences; 0302 clinical medicine; Asian People; Risk Factors; risk factors; Humans; Prospective Studies; incidence density; Aged; Aged, 80 and over; Diabetic Retinopathy; Incidence; Middle Aged; 3. Good health; diabetic retinopathy; Cholesterol; Diabetes Mellitus, Type 2; Hypertension; community; epidemiology; Female

A prospective study was carried out from August 2010 to 2014 in the community of Fengyutan (China). Six hundred and twenty two T2D subjects were collected. The incidence density diabetic retinopathy (DR) 1.81% person-year (95% confidence interval, CI: 1.21–2.43% person-year). After a Cox regression model analysis adjusted confounding factors, independent predictors related DR including male gender (adjusted hazard ratios, aHR: 1.47, 95% 1.21–1.62), with hypertension (aHR: 1.49, 95%: 1.12–1.73), duration diabetes > 10 years 2.28, 2.05–2.42), uncontrolled 1.76, 1.41–2.01), total cholesterol ≥ 200 mg/dL 1.54, 1.34–1.72) HbA1c 7% (mmol/mol) 2.12, 1.87–2.32). Duration revealed significantly dose-response relationship onset DR. Chinese relatively low comparison other studies. More attention should be paid patients, especially gender, hypertension, longer diabetes, 200mg/dL (mmol/mol).