A New Strategy Against Peri-Implantitis: Antibacterial Internal Coating

• DOI: 10.3390/ijms20163897
• Publication Date: 2019-08-09T15:11:31Z
• Authors: Francesco Carinci; Dorina Lauritano; Carlo Alberto Big...; Daniele Pazzi; Valentina Candotto; Paulo Santos de O...; Antonio Scarano
• Keywords: Peri-implantitis; Mucositis; Implant Failure

The bacterial biofilm formation in the oral cavity and microbial activity around implant tissue represent a potential factor on interface between bone fixture that could induce an inflammatory phenomenon generate increased risk for mucositis peri-implantitis. aim of present clinical trial was to investigate quality new antibacterial coating internal chamber vivo at six months. PIXIT (Edierre srl, Genova Italy) is prepared by with alcoholic solution containing polysiloxane oligomers chlorhexidine gluconate 1%. A total 15 healthy patients (60 implants) non-contributory past medical history (nine women men, all non-smokers, mean age 53 years, ranging from 45–61 years) were scheduled receive bilateral fixed prostheses or crown restorations supported fixture. No adverse effects no failure reported four All experimental sites showed good soft healing point times local evidence inflammation observed. Real-Time Polymerase Chain Reaction (PCR) analysis coated uncoated implants decrease count part chamber. bacteria loading (TBL) detected each PCR reaction lower treated (81,038 units/reaction) compared untreated (90,057 (p < 0.01). polymeric chlorhexydine ability control level peri-implant tissue. Moreover, investigation demonstrated able influence also microbiota, particular species involved pathogenesis peri-implantitis are higher long-term dental restoration.