Unveiling the Genomic Features and Biocontrol Potential of Trichoderma hamatum Against Root Rot Pathogens

• DOI: 10.3390/jof11020126
• Publication Date: 2025-02-10T08:39:47Z
• Authors: Yuzhou Feng; Xinyi Shuai; Jili Chen; Qing Zhang; Lijie Jia; Luzhi Sun; Yunxia Su; Yanyan Su; Gangqiang Dong; Tao Liu; Guangqiang Long
• Keywords: Fusarium solani; Root rot; Panax notoginseng

Fusarium species are among the most significant pathogens causing root rot in Panax notoginseng. In this study, a strain of Trichoderma hamatum was isolated from rhizosphere soil P. notoginseng and subjected to whole-genome sequencing. Plate confrontation experiments were conducted investigate antagonistic effects T. against oxysporum, solani, acutatum, primary rot. Whole-genome sequencing revealed 10,774 predicted genes hamatum, which 454 associated with carbohydrate-active enzymes (CAZymes) involved fungal cell wall degradation. Additionally, 11 biosynthetic gene clusters (BGCs) antimicrobial production identified, highlighting biocontrol potential hamatum. plate experiments, showed substantial inhibition rates 68.07%, 70.63%, 66.12% F. respectively. Scanning electron microscopy suggested hyperparasitism characterized by spore that adhered pathogen, thereby inhibiting its growth. These findings provide theoretical foundation enhance understanding biological control mechanisms supporting applications sustainable agriculture.