Inhibition of Foodborne Pathogenic Bacteria by Excreted Metabolites of Serratia marcescens Strains Isolated from a Dairy-Producing Environment

• DOI: 10.3390/microorganisms11020403
• Publication Date: 2023-02-06T09:08:07Z
• Authors: Bernadett Baráti-...; Giseli Cristina D...; Judit Perjéssy; Adél Klupács; Zsolt Zalán; Csilla Mohácsi-Fa...; Ágnes Belák
• Keywords: Prodigiosin; Serratia; Chitinase; Yersinia enterocolitica

Serratia marcescens strains from a dairy-producing environment were tested for their inhibitory effect on Listeria monocytogenes, Salmonella Hartford, Yersinia enterocolitica and Escherichia coli. Inhibition of foodborne pathogens was observed in the case non-pigmented strain, while pigment-producing isolate able to inhibit only Y. enterocolitica. The co-culturing study tryptone soya broth (TSB) milk showed that growth inhibited first 24 h, but later pathogen could grow presence strain even if its cell concentration 1000 times higher than Salmonella. However, we found (1) concentrated cell-free supernatants had stronger activity, which confirms extracellular nature antagonistic compound(s). We proved (2) protease chitinase enzymes can take part this mechanism, they are not main compounds. prodigiosin pigmented strain; thus, (3) hypothesized does inhibition pathogens. (4) combined different metabolites might be attributed property. Application S. supernatant an effective antibacterial strategy food industry, mainly form bio-disinfectant surfaces food-processing areas.