Genetic Insights into Biofilm Formation by a Pathogenic Strain of Vibrio harveyi

• DOI: 10.3390/microorganisms12010186
• Publication Date: 2024-01-17T09:16:56Z
• Authors: Amandine Morot; François Delavat; Alexis Bazire; Christine Paillard; Alain Dufour; Sophie Rodrigues
• Keywords: Vibrio harveyi; Virulence factor; Human pathogen

The Vibrio genus includes bacteria widely distributed in aquatic habitats and the infections caused by these can affect a wide range of hosts. They are able to adhere numerous surfaces, which result biofilm formation that helps maintain them environment. involvement lifestyle virulence pathogens organisms remains be investigated. harveyi ORM4 is pathogen responsible for an outbreak European abalone Haliotis tuberculata populations. In present study, we used dynamic culture technique coupled with laser scanning microscopy characterize formed V. ORM4. We furthermore RNA-seq analysis examine global changes gene expression cells compared planktonic bacteria, identify biofilm- virulence-related genes showing altered expression. A total 1565 were differentially expressed, including associated motility, polysaccharide synthesis, quorum sensing. up-regulation 18 synthesis type III secretion system suggests this factor induced biofilms, providing indirect evidence relationship between virulence.