Curcumin-Added Whey Protein Positively Modulates Skeletal Muscle Inflammation and Oxidative Damage after Exhaustive Exercise

• DOI: 10.3390/nu14224905
• Publication Date: 2022-11-21T09:13:36Z
• Authors: Kelly Aparecida Dias; Aline Rosignoli d...; Stephanie Micheli...; Lívya Alves Oliveira; João Vitor da Sil...; Roberto Sousa Dias; Sérgio Oliveira d...; Antônio José Natali; Sérgio Luis Pinto...; Reggiani Vilela G...; Elad Tako; Hercia Stampini D...; Ceres Mattos Dell...
• Keywords: Muscle tissue

(1) Background: Exhaustive exercise can induce muscle damage. The consumption of nutritional compounds with the ability to positively influence oxidative balance and an exacerbated inflammatory process has been previously studied. However, little is known about value curcumin (CCM) when mixed whey protein concentrate (WPC). This study was developed evaluate effect CCM-added WPC on control histopathological consequences in tissue submitted exhaustive swimming test (ET). (2) Methods: 48 animals were randomly allocated six groups (n = 8). An ET performed 4 weeks after start diet euthanized 24 h post ET. (3) Results: + CCM reduced IL-6 increased IL-10 expression tissue. carbonyl compared standard AIN-93M diets. Higher nitric oxide concentrations observed that consumed CCM. Consumption or isolated areas infiltrate fibrotic muscle. (4) Conclusions: contribute reduction inflammation damage caused by test.