Unlocking the Hidden Genetic Diversity of Varicosaviruses, the Neglected Plant Rhabdoviruses

• DOI: 10.3390/pathogens11101127
• Publication Date: 2022-09-30T03:09:29Z
• Authors: Nicolas Bejerman; Ralf G. Dietzgen; Humberto Debat
• Keywords: 0301 basic medicine; Varicosaviruses; genome architecture; Plant Rhabdoviruses; Taxonomía; Genome Architecture; metatranscriptomics; Rhabdovirus de las Plantas; R; Taxonomía de Virus; virus taxonomy; Virus Taxonomy; Article; 3. Good health; 03 medical and health sciences; varicosaviruses; plant rhabdovirus; Medicine; Taxonomy; Metatranscriptomics; plant rhabdovirus; varicosaviruses; genome architecture; virus taxonomy; metatranscriptomics

The genus Varicosavirus is one of six genera plant-infecting rhabdoviruses. Varicosaviruses have non-enveloped, flexuous, rod-shaped virions and a negative-sense, single-stranded RNA genome. A distinguishing feature varicosaviruses, which shared with dichorhaviruses, bi-segmented Before 2017, sole varicosavirus was known characterized, then two more varicosaviruses were identified through high-throughput sequencing in 2017 2018. More recently, the number has substantially increased concert extensive use platforms data mining approaches. novel revealed not only sequence diversity, but also plasticity terms genome architecture, including virus tentatively unsegmented Here, we report discovery 45 genomes publicly available metatranscriptomic data. identification, assembly, curation raw Sequence Read Archive reads resulted 39 viral sequences full-length coding regions 6 nearly complete regions. highlights obtained include eight genomes, are linked to phylogenetic clade associated gymnosperms. These findings most phylogeny date shed new light on relationships evolutionary landscape this group plant Thus, for allowed us unlock hidden genetic diversity largely neglected