Missed Opportunities for HIV Diagnosis and Their Clinical Repercussions in the Portuguese Population—A Cohort Study

• DOI: 10.3390/pathogens13080683
• Publication Date: 2024-08-13T14:54:54Z
• Authors: João Lourinho; Maria João Miguel; Frederico Gonçalves; Francisco Vale; Cláudia Silva Franco; Nuno Marques
• Keywords: HIV diagnosis

Late human immunodeficiency virus (HIV) diagnosis has been associated with missed opportunities for earlier diagnosis. We conducted a retrospective, longitudinal, single-centre cohort study evaluating these and their clinical repercussions in adults new HIV or who were drug-naïve, attended our Infectious Diseases Department between 2018 2023. assessed the two years prior to after last negative test. compared laboratorial data from individuals without opportunities. The primary outcome considered was AIDS-defining conditions at Among 436 included individuals, 27.1% experienced least one opportunity. Those more likely be female (p = 0.007), older first consultation < 0.001), born Africa 0.001) countries high prevalence have heterosexual transmission 0.001). adjusted analysis showed that significantly (OR 3.23, CI 95% [1.62–6.46], p These findings highlight impact of on severity, underscoring need targeted interventions reduce them.