Management of Periodontal Disease with Adjunctive Therapy with Ozone and Photobiomodulation (PBM): A Randomized Clinical Trial

• DOI: 10.3390/photonics9030138
• Publication Date: 2022-02-28T01:48:33Z
• Authors: Andrea Scribante; Simone Gallo; Maurizio Pascadopoli; Riccardo Soleo; Fabio Di Fonso; Luca Politi; Adith Venugopal; Anand Marya; Andrea Butera
• Keywords: Bleeding on probing; Ozone Therapy; Debridement (dental)

Periodontitis is an inflammatory condition of the soft and hard tooth-supporting tissues, representing first cause tooth loss. In addition to standard mechanical debridement (Scaling Root Planing, SRP), further approaches have been proposed as adjuncts. The aim present randomized clinical trial compare efficacy ozone or photobiomodulation (PBM) therapy in SRP treat periodontal disease. According a split-mouth design, 240 pathological sites, corresponding 30 patients, were randomly divided according professional oral hygiene protocol performed at baseline (T0) after 1 (T1), 2 (T2), 3 (T3), 4 (T4), 5 (T5), 6 (T6) months. A total 120 sites underwent ozonized water administration (ozone group), whereas other treated with (PBM both SRP. At every timepoint, following indexes assessed: Probing Pocket Depth (PPD) (measured on six per element), Plaque Index (PI), Bleeding (BOP). As regards PPD, significant intergroup differences noticed from T5, significantly lower values PBM group (p < 0.05), where decreased T6 0.05). Both PI BoP generally groups; difference was found between T0 T1 among groups progressively higher reduction time frames study, despite comparisons not being > appear be effective adjuvant treatments SRP, obtaining slightly better outcome for latter long term, T5 PPD. However, because absence standardized protocols considering therapeutic research purposes, no definitive conclusions can reached, studies are required.