Selective Surface Acoustic Wave-Based Organophosphorus Sensor Employing a Host-Guest Self-Assembly Monolayer of β-Cyclodextrin Derivative

• DOI: 10.3390/s150817916
• Publication Date: 2015-07-23T14:06:15Z
• Authors: Yong Pan; Ning Mu; Shengyu Shao; Liu Yang; Wen Wang; Xiao Xie; Shitang He
• Keywords: Imprinting (psychology); Molecular imprinting

Self-assembly and molecular imprinting technologies are very attractive for the development of artificial recognition systems provide chemical based on need not happenstance. In this paper, we employed a b-cyclodextrin derivative surface acoustic wave (SAW) sensor detecting warfare agents (CWAs) sarin (O-Isoprophyl methylphosphonofluoridate, GB). Using acid (isoprophyl hydrogen methylphosphonate) as an template, mono[6-deoxy-6-[(mercaptodecamethylene)thio]]-β-cyclodextrin was prepared by self-assembled method one SAW oscillators. After templates' removal, sensitive selective (MIP) monolayer GB prepared. Electrochemical impedance spectroscopy atomic force microscope (AFM) were used to characterize film. Comparing detection results MIP film non-MIP film, molecularly effect also proved. The resulting could detect low 0.10 mg/m3 at room temperature frequency shift about 300 Hz. response increased linearly with increasing concentration in range 0.7 mg/m3~3.0 mg/m3. When detected under different temperatures, exhibited outstanding sensitivity reliability.