Botulinum Neurotoxin Injections in Childhood Opisthotonus

• DOI: 10.3390/toxins13020137
• Publication Date: 2021-02-13T03:41:25Z
• Authors: Mariam Hull; Mered Parnes; Joseph Jankovic
• Keywords: Botulinum neurotoxin; Etiology; Neurotoxin; Baclofen

Opisthotonus refers to abnormal axial extension and arching of the trunk produced by excessive contractions paraspinal muscles. In childhood, posture is most often related dystonia in setting hypoxic injury or a number other acquired genetic etiologies. The condition painful, interferes with ambulation quality life, challenging treat. Therapeutic options include oral benzodiazepines, intrathecal baclofen, botulinum neurotoxin injections, deep brain stimulation. Management opisthotonus within pediatric population has not been systematically reviewed. Here, we describe series seven children who presented our institution whom symptom relief was achieved following administration injections.