Cytological and cytochemical diagnosis of sideroblastic anemia

• DOI: 10.35754/0234-5730-2024-69-1-80-88
• Publication Date: 2024-03-19T17:08:30Z
• Authors: V. N. Dvirnyk; A. V. Kohno; A. A. Chulkova; I. N. Naumova; O. V. Lazareva; E. N. Parovichnikova
• Keywords: Sideroblastic anemia

Introduction . Disruption of iron utilization by erythrocaryocytes with deposition hemosiderin granules in the form a ring is pathognomonic sign sideroblastic anemia. An integral part diagnosis this type anemia cytomorphological analysis bone marrow aspirate cytochemical reaction to sideroblasts. Aim — present current methods cytological and Main findings A presence sideroblasts marrow. Ring are considered be intramitochondrial located around nucleus. It only possible diagnose using special diagnostics, but carried out half laboratories that hematological diseases Russian Federation. The algorithm laboratory diagnostics National Medical Research Center for Hematology presented.