Antibacterial substances of sponges, Agelas tubulata and Phyllospongia sp., from Manado Bay, against the growth of several bacterial strains

• DOI: 10.35800/jasm.5.1.2017.24253
• Publication Date: 2019-09-23T02:40:42Z
• Authors: Nani I.J Undap; Deiske A Sumilat; Robert Bara
• Keywords: Staphylococcus saprophyticus

Title (Bahasa Indonesia): Senyawa antibakteri spons, Agelas tubulata dan Phyllospongia sp., dari Perairan Teluk Manado, terhadap pertumbuhan beberapa strain bakteri tubulataand Phyllospongiasp. are marine spongethat contain active compoundsthat have potential to beantibacterial, anticancer and antifungal which not been used. This study was aimed examine the sponge extracts inhibitbacterial growth, i.e. Pseudomonas aeruginosa, Proteus mirabilis, Staphylococcus aureus, Escherichia coli, S. saprophyticus andtoanalyze fraction of antibacterial component using bio-autographic method. were collected from Manado Bayand method used in Agar Diffusion Method. Results showed that A. extract had activity against all 5 bacteria tested. tubulataextract inhibition zone withbroader spectrum than extract, while has specifity forP. mirabilis.Agelas danPhyllospongia sp. merupakan spesies spons laut yang mengandung senyawa aktif berpotensi antibakteri, antikanker antijamur belum banyak dimanfaatkan. Penelitian ini bertujuan untuk menguji ekstrak menghambat yaitu Eschericia colidan menganalisis fraksi melalui teknik bioautografi. Spesies diambil Pantai Malalayang Manado. Metode digunakan metode difusi agar. Hasil penelitian ini, tubulatadan mempunyai aktivitas uji. EkstrakA. tubulatamemiliki daya hambat dengan spektrum lebih luas dibandingkan Phyllospongiasp.sedangkanekstrak sp.memiliki spesifitas P. mirabilis.