Comparative Analysis of Acid-base Status Parameters in Newborn with Congenital Surgical Malformations During Perioperative Care Based on Types of Anesthesia

• DOI: 10.36013/jimsa.v2i1.50
• Publication Date: 2021-02-13T07:47:53Z
• Authors: Oleksii Vlasov
• Keywords: Surgical stress

Introduction: Congenital malformations (CM) are most common in newborns and infants the first year of life require surgical correction hours, days, months life. Surgical interventions severely ill babies with can lead to catabolic stress, circulatory respiratory disorders, metabolism shifts, water-electrolyte, protein, acid-base status disorders.
 This study aimed compare congenital pathology under different types combined anesthesia. 
 Materials methods: retrospective included 150 CM who required surgery. The patients were divided into three groups based on provided anesthesia: inhalation by Sevoran (sevoflurane) regional anesthesia (group I); intravenous Fentanyl II); combination 20% Sodium Oxybutyrate III). analysis included: status, peripheral oximetry, need for an oxygen mixture inhaled patient.
 Results In group I, there was a significant reduction partial tension CO2 increased pH from pre-surgical at time induction anesthesia, during painful, traumatic stage, after surgery compared II III. Peripheral O2 saturation not critically reduced all stages observation except I III stage (97.79 ± 2.45 vs. 98.79 1.63, p = 0.0194) painful period (96.29 3.47 98.10 2.47, 0.0368). higher concentrations mixture. There difference FiO2 between (0.47 0.29 0.33 0.2, 0.0071), immediately (0.34 0, 19 0.26 0.13, 0.0246).
 Conclusion: Among requiring intervention substantial changes observed where (Group I).