EVALUATION OF ANTIMICROBIAL, ANTIOXIDANT AND ENZYME INHIBITION ROLES OF POLAR AND NON-POLAR EXTRACTS OF CLITORIA TERNATEA SEEDS

• DOI: 10.36899/japs.2021.5.0342
• Publication Date: 2021-01-25T17:50:00Z
• Authors: Z Mushtaq; U Khan; N Seher; M Shahid; M.T. Shahzad; A.A. Bhatti; T Sikander
• Keywords: Clitoria ternatea

Clitoria ternatea is one of the medicinal plants fabaceae family that have been traditionally useful in herbal medicine.In present study, invitro antimicrobial, antioxidant and enzyme inhibition assay polar non-polar extracts/fractions seeds were evaluated.The antimicrobial activity was done by well diffusion while MIC serial dilution method.Crude ethanolic extract showed maximum antibacterial against B. subtilus (17.6 mm ±0.17).Ethyl acetate at 0.156 μg/mL E. coli.In addition, Crude methanolic antifungal Aspergillus parasiticus (16 ±0.27).The DPPH FRAP assay.Crude (86.26%) crude exhibit reducing power 370.19 % ± 20.50.Moreover, n-hexane possessed highest phenolic content (272.16 17.96 GAE µg/g), flavonoid (275.5 8.24 µg/g).The observed (α-amylase), water-soluble residue exhibited 50% pepsin inhibition.The results concluded most obtained from significant biological activities can act as promising source natural therapeutic agents be used for future drug developmental studies.