A randomized controlled study on carbon dioxide insuffiation during ERCP

• DOI: 10.3760/cma.j.issn.1007-5232.2011.12.003
• Publication Date: 2011-12-20
• Authors: Ying Huang; Hong xiang Gu; Zhi-hui Guo; Ling Jiang; Qing-wen Zheng; Yang Bai; Bo Jiang
• Keywords: Vital signs; Oxygen Saturation

Objective To investigate the safety and efficacy of carbon dioxide （ CO2 ） insufflation during ERCP. Methods Between January August 2011, a total 102 consecutive patients who underwent ERCP were randomized to accept insuffiation n = 52） air 50） procedure. was carried out with same instrument by an expert endoscopist blinded gas used procedure controlled at 30 minutes 1 hour. The heart rate, oxygen saturation patient continuously monitored Before hour after end operation, abdominal X-ray taken evaluate width intestine, degree intesti- nal expansion defined as normal, mild, moderate severe according increased. A ques- tionnaire 100 mm visual analogue scale （VAS） quantify pain distention experienced hour, 2 hours, 6 hours patients＇ vital signs, bowel dilatation, average operating time, score on VAS, complications in groups analyzed. Results baseline characteristics comparable. successfully performed all no complication observed. In group, mean rate （45.2 ± 10.6） min, （102.2 10.3） bpm （99.5 0.5）%, which （48.5 ±11.2） （100.3 ±11.4） （98.9 ±0.6）%, respectively, group. There significant differences these items between P 〉 0. 05 ）. Moderate intestinal found 14 （26. 9% group 28 （56. 0% latter significantly higher than former （X2 11.61, 009）. Both scores post-ERCP lower those but without difference （P 0.05 However, （7.4 ±2. vs. 18. 7 ±4. post-ERCP, 9.6 ±3.7 20. ±-4. 5 〈 O. Similarly, post-ER- CP （7. ±-3. 3 8.9 3.7 19. 4 4. Conclusion use instead appears be safe. lnsufflation palliates expansion, comparison air. because single-center clinical observation limited number cases, C02 requires further evaluated.

Key words: Cholangiopancreatography, endoscopic retrograde; Carbon dioxide; Abdominal ; distension