Association between the Blautia/Bacteroides Ratio and Altered Body Mass Index after Bariatric Surgery

• DOI: 10.3803/enm.2022.1481
• Publication Date: 2022-06-30T01:45:03Z
• Authors: Yoonhong Kim; Dooheon Son; Bu Kyung Kim; Ki Hyun Kim; Kyung Won Seo; Kyoungwon Jung; Seun Ja Park; Sanghyun Lim; Jae Hyun Kim
• Keywords: Bacteroides fragilis

Current evidence support that the gut microbiota plays a potential role in obesity. Bariatric surgery can reduce excess weight and decrease risk of life-threatening weight-related health problems may also influence microbiota. In this study, we aimed to investigate changes before after bariatric evaluate association microbial shift altered body mass index (BMI) surgery.Between January 2019 July 2020, stools from 58 patients scheduled for were collected. Six months surgery, 22 these re-collected, evaluated. addition, differences between with severe obesity (BMI >35 kg/m2, n=42) healthy volunteers normal BMI (18.8 22.8 n=41) investigated.The who underwent showed increased α-diversity differed β-diversity compared those surgery. Interestingly, Blautia was decreased Bacteriodes at genus level Further, Blautia/Bacteroides ratio positive correlation BMI. To validate results, severely obese high demonstrated correlated positively BMI.In analysis presented had changed