Evaluation of preeclampsia outcomes in de novo preeclampsia and superimposed preeclampsia: A case-control study from a tertiary center

• DOI: 10.38136/jgon.1440611
• Publication Date: 2024-06-24T12:19:47Z
• Authors: Göksun İpek; Atakan Tanacan; Zahid Ağaoğlu; Ayça Peker; Gülcan Okutucu; Dilek Sahin
• Keywords: süperempoze preeklampsi;preeklampsi sonuçları;olumsuz gebelik sonuçları;kronik hipertansiyon; 03 medical and health sciences; 0302 clinical medicine; Obstetrics and Gynaecology; superimposed preeclampsia;preeclampsia outcomes;adverse outcomes;chronic hypertension; Kadın Hastalıkları ve Doğum

Objective: To compare de novo and superimposed preeclampsia outcomes and evaluate the role of chronic hypertension in preeclampsia outcomes Methods: The present retrospective case-control study was conducted on 250 pregnant women diagnosed with preeclampsia, including 100 patients in the superimposed preeclampsia group, 150 in the de novo preeclampsia group. The control group comprised 200 low-risk pregnant women consecutively delivered in the same timeline. De novo and superimposed preeclampsia groups’ demographic specialties and obstetric and neonatal outcomes were compared with the control group and also compared between preeclampsia groups. Parameters were then evaluated with the literature findings. Results: Early onset preeclampsia and preterm delivery rates were higher in the superimposed preeclampsia group , with p-values 0.046 and 0.026, respectively, The presence of prodromal symptoms was lower in the superimposed preeclampsia group than in the de novo preeclampsia group (p=0.029). Fetal growth retardation was higher in both preeclampsia groups then in the control group with a p-value of