An eight-year study of Shigella species in Beijing, China: serodiversity, virulence genes, and antimicrobial resistance

• DOI: 10.3855/jidc.3692
• Publication Date: 2014-07-14T14:30:02Z
• Authors: Mei Qu; Xin Zhang; Guirong Liu; Ying Huang; Lei Jia; Weili Liang; Xitai Li; Xiaona Wu; Jie Li; Hanqiu Yan; Biao Kan; Quanyi Wang
• Keywords: Shigella boydii; Shigella sonnei

Introduction: This study was conducted to determine the prevalence of serotypes, virulence factors, and antimicrobial resistance patterns Shigella spp. in Beijing, China, from 2004 2011. Methodology: Real-time PCR assays were used detect virulent genes, Kirby-Bauer disk diffusion method evaluate resistance. Results: Among total 1,652 isolates, S. sonnei (57.1%) predominant species, followed by flexneri (42.3%), dysenteriae (0.4%), boydii (0.2%). Nineteen serotypes discovered among strains. The gene ipaH most frequent, sen set. presence set showed significant difference two dominant serogroups, sonnei. Over 90% isolates at least three drugs with widened spectrum. High-level single multiple antibiotics more common than flexneri. Conclusion: There an obvious serotype change a dramatic increase antibiotic Beijing.