Prevalence of ESBL-producing Enterobacteriaceae isolated from blood cultures in Mali

• DOI: 10.3855/jidc.7536
• Publication Date: 2016-10-31T17:36:00Z
• Authors: Samba Adama Sangare; Almoustapha Issia...; Ibrehima Guindo; Aminata Maiga; Namory Camara; Oumar Agaly Dicko; Souleymane Diallo; Flabou Bougoudogo; Laurence Armand-L...; Antoine Andremont; Ibrahim Izetiegou...
• Keywords: Amikacin; Blood Culture

The increasing frequency of extended-spectrum beta-lactamase (ESBL)-producing Enterobacteriaceae is becoming a serious public health concern. This study sought to determine ESBL in isolated from patients' blood cultures two university teaching hospitals Bamako, Mali.During three-month period, the presence patients admitted Bamako was evaluated. microbial identifications were initially performed with an API 20E gallery and VITEK2 locally Mali, then confirmation France mass spectrometry MALDI-TOF bacteriology laboratory hospital Bichat. Antibiotic susceptibility profiles determined by diffusion method as recommended European Committee on Antimicrobial Susceptibility Testing (EUCAST).The species K. pneumoniae (14/40; 35.0%), E. coli (11/40; 27.5%), cloacae (9/40; 22.5%). Of strains isolated, 21/34 (61.8%) had phenotype, including 10/14 (71.4%) pneumoniae, 8/11 (72.7%) coli, 3/9 (33.3%) cloacae. Resistances associated follows: gentamicin (10/10, 100%; 6/8, 75%; 2/3, 67%, respectively), amikacin (2/10, 20%; 0/8, 0%; 0/3, 0%, ofloxacin (8/10, 80%; 7/8, 87%; 3/3, 100%, cotrimoxazole respectively).Almost two-thirds our producers. Only susceptibilities carbapenems fully conserved within strains.