Post‑infectious ST elevation myocardial infarction following a COVID‑19 infection: A case report

• DOI: 10.3892/br.2021.1493
• Publication Date: 2021-12-15T07:35:30Z
• Authors: Manuela Ceccarelli; Andrea Marino; Federica Cosentino; Vittoria Moscatt; Benedetto Celesia; Maria Gussio; Roberto Bruno; Emmanuele Rullo; Giuseppe Nunnari; Bruno Cacopardo
• Keywords: ST-segment elevation myocardial infarction; post-infectious sequelae; 0301 basic medicine; 0303 health sciences; 03 medical and health sciences; COVID-19; Severe Acute Respiratory Syndrome-Coronavirus-2; COVID-19; Post-infectious sequelae; Severe Acute Respiratory Syndrome-Coro-navirus-2; ST-segment elevation myocardial infarction; 3. Good health

Severe Acute Respiratory Syndrome-Coronavirus-2 (SARS-CoV-2) has been shown to increase the risk of thrombotic events due to a hypercoagulable state caused by several factors. The case of a 59-year-old woman affected by hypertension and metabolic disorders, treated for a COVID-19 infection who developed cardiac symptoms during the first days of hospitalization is reported. Electrocardiogram analysis and cardiac-ultrasound confirmed ST-segment elevation myocardial infarction (STEMI) diagnosis, thus the patient underwent percutaneous coronary intervention, which was successful. This case highlights a possible association between respiratory infection, particularly SARS-CoV-2 infection, and cardiovascular events, in particular Acute Coronary Syndrome. The association between these phenomena seems related to a range of factors, including a proinflammatory state and the hypoxemia. Moreover, the association amongst SARS-CoV-2 and cardiovascular diseases may be also linked to long-term sequelae. Thus, further studies are required to better under-stand the multifaceted and severe complications of this disease.