The optimum marker for the detection of lymphatic vessels

• DOI: 10.3892/mco.2017.1356
• Publication Date: 2017-07-31T09:20:00Z
• Authors: Ling-Ling Kong; Nian-Zhao Yang; Liang-Hui Shi; Guo-Hai Zhao; Wenbin Zhou; Qiang Ding; Ming-Hai Wang; Yi-Sheng Zhang
• Keywords: Lymphangiogenesis; Podoplanin; Lymphatic vessel; Lymphatic Endothelium

Podoplanin, lymphatic vessel endothelial hyaluronic acid receptor-1, prospero-related homeobox-1 and vascular growth factor receptor 3 have been demonstrated to crucial roles in the development of system lymphangiogenesis process by combining with their corresponding receptors. Thus, four markers widely used labelling vessels for detection invasion. Numerous authors aimed identify these mechanisms partly clarified at molecular level. The aim present review was comprehensively clarify characteristics latent action modes order determine which is best one