Intravoxel incoherent motion magnetic resonance imaging for breast cancer: A comparison with benign lesions and evaluation of heterogeneity in different tumor regions with prognostic factors and molecular classification

• DOI: 10.3892/ol.2018.9312
• Publication Date: 2018-08-16T08:18:00Z
• Authors: Ming Zhao; Kuang Fu; Lei Zhang; Wenhui Guo; Qiong Wu; Xue Bai; Ziyao Li; Qiang Guo; Jiawei Tian
• Keywords: Intravoxel incoherent motion

The objective of the present study was to compare differentiation between breast cancer and benign lesions regional distribution characteristics in various subtypes using intravoxel incoherent motion (IVIM) parameters. This retrospective involved 119 patients with 22 lesions, who underwent 3.0T magnetic resonance imaging examinations. apparent diffusion coefficient (ADC) IVIM parameters (slow ADC, fast ADC fraction ADC) were obtained from diffusion-weighted (DWI) b-values 0, 50, 100, 150, 200, 400, 500, 1,000 1,500 sec/mm2. Compared exhibited decreased (P<0.001), slow (P<0.001) values, higher values. Tumors metastatic axillary lymph nodes demonstrated increased values compared tumors without nodes. Fast tumor tissues estrogen receptor (ER) progesterone (PR) negative groups than positive lower ER PR (P<0.001). Luminal B (HER2- negative) peritumor comparison other subtypes. Triple-negative (TNBC) tissue when TNBC edge had (P<0.01) (P<0.05). Therefore, tumor, may be useful for assess invasive extent tumors.