Calcitonin-negative neuroendocrine tumor of thyroid gland mimicking anaplastic carcinoma: an unusual entity.

• DOI: 10.3978/j.issn.2227-684x.2015.01.02
• Publication Date: 2015-08-01
• Authors: Onur İsmi; Rabia Bozdoğan Ar...; Mustafa Berkeşoğlu; Ahmet Dağ; Emel Sezer; Kemal Koray Bal; Yusuf Vayısoğlu
• Keywords: Synaptophysin; Chromogranin A; Anaplastic carcinoma; Medullary carcinoma

Medullary thyroid cancer is the neuroendocrine tumor (NET) of with mostly both secreting calcitonin and immunohistochemically showing positivity. Occasionally; NETs may have little or no expression. We present a case serum negative calcitonin-negative staining positive reaction to markers synaptophysin chromogranin-A. The patient's right vocal cord was paralytic mass huge descending thorax till hilar region. discussed diagnostic difficulties way treatment about light current literature this case.