A Highly Sensitive and Specific FDCD Method for Chirality Analysis of Naturally Occurring Pteridines

• DOI: 10.3987/com-01-s(k)56
• Publication Date: 2009-03-09T04:10:29Z
• Authors: Shizuaki Murata; Ning Chen; Kazuhisa Ikemoto; Takashi Sugimoto; Hiroshi Ichinose; Toshiharu Nagatsu
• Keywords: 0303 health sciences; 03 medical and health sciences; 540

Absolute configurations of 6-(1-hydroxyalkyl)pterin derivatives are determined by fluorescence detected circular dichroism (FDCD) spectroscopy. This method is at least 10 times more sensitive than CD analysis and specificeven existence of 10 times excess amounts of chiral sugars or nucleic acids.