Salaprionol and Ponkoranol with Thiosugar Sulfonium Sulfate Structure from Salacia prinoides and a-Glucosidase Inhibitory Activity of Ponkoranol and Kotalanol Desulfate

• DOI: 10.3987/com-07-11315
• Publication Date: 2009-02-16T02:15:56Z
• Authors: Masayuki Yoshikawa; Fengming Xu; Seikou Nakamura; Tao Wang; Hisashi Matsuda; Genzoh Tanabe; Osamu Muraoka
• Keywords: Sulfonium

The methanolic extract from the roots and stems of Indian Salacia prinoides its water-eluted fraction Diaion HP-20 column were found to exhibit inhibitory activities against α-glucosidase.From fraction, two new unique constituents with thiosugar sulfonium sulfate, salaprinol (1) ponkoranol (2), isolated together 10 known including salacinol kotalanol.The structures 1 2 elucidated on basis