Pulmonary Alveolar Microlithiasis: CT and pathologic findings in 10 patients

• DOI: 10.4081/monaldi.2005.659
• Publication Date: 2016-07-04T03:06:49Z
• Authors: H. Sumikawa; T. Johkoh; N. Tomiyama; S. Hamada; M. Koyama; M. Tsubamoto; S. Murai; A. Inoue; H. Nakamura; T. Tachibana; N.L. Müller
• Keywords: Parenchyma

To evaluate CT findings of pulmonary alveolar microlithiasis and correlate the with pathologic findings.The study included 10 patients pathologically proven microlithiasis. Two independent observers evaluated presence, extent distribution findings. were compared those at autopsy in two transbronchial biopsy eight patients.All had a myriad calcified nodules measuring approximately 1 mm diameter. Close apposition resulted areas ground-glass attenuation consolidation, which predominant abnormality on all patients, involving 41% +/- 16.3 (mean SD) 30% 4.8 lung parenchyma, respectively. Calcifications also seen along interlobular septa, bronchovascular bundles pleura. Other septal thickening, thickening bundles, nodules, subpleural cysts. There was solid agreement between for presence (kappa value; 0.77) (Spearman rank correlation; r = 0.81 to 1.0 p < 0.01) abnormalities. Autopsy specimens demonstrated microliths airspaces Subpleural small cysts shown represent dilated ducts.Pulmonary is characterised by numerous small, calcifications pleura, opacities, The ducts.