Consensus Recommendations for the Clinical Application of Repetitive Transcranial Magnetic Stimulation (rTMS) in the Treatment of Depression
Consensus
Major Depressive Disorder
Clinical Sciences
Clinical Trials and Supportive Activities
610
Clinical sciences
Medical and Health Sciences
03 medical and health sciences
0302 clinical medicine
Clinical Research
Humans
National Network of Depression Centers rTMS Task Group
Psychiatry
Depressive Disorder
Biomedical and Clinical Sciences
Depression
Contraindications
Psychology and Cognitive Sciences
Major
Serious Mental Illness
Mental Illness
Transcranial Magnetic Stimulation
Brain Disorders
3. Good health
Psychiatry and Mental health
Mental Health
American Psychiatric Association Council on Research Task Force on Novel Biomarkers and Treatments
Mental health
DOI:
10.4088/jcp.16cs10905
Publication Date:
2017-05-22T20:19:06Z
AUTHORS (18)
ABSTRACT
Objective To provide expert recommendations for the safe and effective application of repetitive transcranial magnetic stimulation (rTMS) in the treatment of major depressive disorder (MDD). Participants Participants included a group of 17 expert clinicians and researchers with expertise in the clinical application of rTMS, representing both the National Network of Depression Centers (NNDC) rTMS Task Group and the American Psychiatric Association Council on Research (APA CoR) Task Force on Novel Biomarkers and Treatments. Evidence The consensus statement is based on a review of extensive literature from 2 databases (OvidSP MEDLINE and PsycINFO) searched from 1990 through 2016. The search terms included variants of major depressive disorder and transcranial magnetic stimulation. The results were limited to articles written in English that focused on adult populations. Of the approximately 1,500 retrieved studies, a total of 118 publications were included in the consensus statement and were supplemented with expert opinion to achieve consensus recommendations on key issues surrounding the administration of rTMS for MDD in clinical practice settings. Consensus process In cases in which the research evidence was equivocal or unclear, a consensus decision on how rTMS should be administered was reached by the authors of this article and is denoted in the article as "expert opinion." Conclusions Multiple randomized controlled trials and published literature have supported the safety and efficacy of rTMS antidepressant therapy. These consensus recommendations, developed by the NNDC rTMS Task Group and APA CoR Task Force on Novel Biomarkers and Treatments, provide comprehensive information for the safe and effective clinical application of rTMS in the treatment of MDD.
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