Cardiovascular Outcomes according to Comorbidities and Low-Density Lipoprotein Cholesterol in Korean People with Type 2 Diabetes Mellitus

• DOI: 10.4093/dmj.2021.0344
• Publication Date: 2023-01-27T00:48:16Z
• Authors: Min Kyong Moon; Junghyun Noh; Eun-Jung Rhee; Sang Hyun Park; Hyeon Chang Kim; Byung Jin Kim; Hae Jin Kim; Seonghoon Choi; Jin Oh Na; Young Youl Hyun; Bum Joon Kim; Kyung-Do Han; In-Kyung Jeong
• Keywords: Adult; Cardiovascular Diseases* / prevention & control; Type 2* / epidemiology; korea; 610; Diseases of the endocrine glands. Clinical endocrinology; LDL; 03 medical and health sciences; 0302 clinical medicine; Risk Factors; 616; Republic of Korea; Diabetes Mellitus; Cardiovascular Diseases* / epidemiology; Humans; dyslipidemias; Republic of Korea / epidemiology; Dyslipidemias; Aged; Korea; Type 2* / complications; cholesterol; Cholesterol, LDL; Hypertension* / epidemiology; Middle Aged; RC648-665; Hypertension* / complications; cardiovascular diseases; Cholesterol; Cardiovascular diseases; Diabetes Mellitus, Type 2; Cardiovascular Diseases; diabetes mellitus; Hypertension; Original Article

There are no clear data to support the cardiovascular (CV) risk categories and low-density lipoprotein cholesterol (LDL-C) treatment goals in Korean people with type 2 diabetes mellitus (T2DM). We evaluated incidence of disease (CVD) according comorbidities suggested LDL-C T2DM nationwide cohort data. Using National Health Insurance Service database, 248,002 aged 30 90 years who underwent routine health check-ups during 2009 were included. Subjects previous CVD excluded from study. The primary outcome was incident CVD, defined as a composite myocardial infarction ischemic stroke follow-up period 2018. mean age study participants 59.6±10.9 years, median 9.3 years. increased order DM duration 5 or more (12.04/1,000 person-years), hypertension (HT) (12.27/1,000 personyears), three CV factors (14.10/1,000 chronic kidney (18.28/1,000 person-years). linearly an level ≥70 mg/dL most patients T2DM. In without HT less than ≥100 mg/dL. For prevention adults T2DM, it can be helpful lower targets when there disease, HT, long mellitus, factors.