Isolated clival metastasis as the cause of abducens nerve palsy in a patient of breast carcinoma: A rare case report

• DOI: 10.4103/0301-4738.158096
• Publication Date: 2015-06-04T12:04:21Z
• Authors: Akhil Kapoor; Vimla Beniwal; Surender Beniwal; Harsh Mathur; HarvindraSingh Kumar
• Keywords: Advanced glaucoma; retina; Biopsy; nasolacrimal duct obstruction; Eye; Deep anterior lamellar keratoplasty; intra-arterial chemotherapy; macular coloboma differentials; lacrimal surgery; Basal encephalocele; 0302 clinical medicine; dengue maculopathy; ligneous conjunctivitis; Macular GHPC; primary acquired nasolacrimal duct obstruction; diplopia; papillary formation; Abducens palsy; meibomian gland; Carcinoma, Ductal, Breast; RE1-994; Magnetic Resonance Imaging; 3. Good health; clival metastasis; Klebsiella pneumoniae; spectral domain optical coherence tomography; optic disc pit with maculopathy; residents; Dragged disc; Female; spectral domain; diabetic macular edema; Brief Communications; Dacryocystorhinostomy; Abducens Nerve Diseases; Adult; tumor; retinal nerve fiber layer thickness; Corvis ST; Breast Neoplasms; Emergence; Skull Base Neoplasms; retinoblastoma; intubation; meibomian gland microenvironment; Juvenile colloid milia; 03 medical and health sciences; breast cancer; Rare Diseases; pulse cyclophosphamide; macular coloboma; Humans; survey; vernal keratoconjunctivitis; retinal genetics; reproducibility; Cytokine; optical coherence tomography; serpiginous choroidopathy; postoperative keratitis; Contact lens; photoreceptor; Confocal microscopy; Ophthalmology; mitomycin-C; pseudomembranous conjunctivitis; Cranial Fossa, Posterior; genetic blueprint; surgical training; Dengue foveolitis; intraocular pressure; cleft lip and palate

Metastatic lesions to the clivus have been reported in various cancers including lung cancer, prostate carcinoma, skin melanoma, and hepatocellular carcinoma. There have been only a few reports of breast cancer presenting with isolated clival metastasis. We report a case of 35-year-old lady, who was known case of breast carcinoma presented with diplopia as the only sign of clival metastasis. The etiology was established by magnetic resonance imaging which showed an enhancing lesion in the clivus. The diagnosis of clival metastasis from breast cancer was confirmed by transsphenoidal biopsy.