Mortality following bone metastasis and skeletal-related events among patients 65 years and above with lung cancer: A population-based analysis of U.S. Medicare beneficiaries, 1999-2006

• DOI: 10.4103/0970-2113.106127
• Publication Date: 2013-01-16T09:41:36Z
• Authors: Nalini Sathiakumar; Elizabeth Delzell; MichaelA Morrisey; Carla Falkson; Mellissa Yong; Victoria Chia; Justin Blackburn; Tarun Arora; MeredithL Kilgore
• Keywords: SEER; Diseases of the respiratory system; 03 medical and health sciences; 0302 clinical medicine; distant stage; RC705-779; Original Article; Claims; fractures; mortality; 3. Good health

To quantify the impact of bone metastasis and skeletal-related events (SREs) on mortality among older patients with lung cancer.Using linked Surveillance, Epidemiology End Results-Medicare database, we identified aged 65 years or diagnosed cancer between July 1, 1999 December 31, 2005 followed them to determine deaths through 2006. We classified as having possible SREs using discharge diagnoses from inpatient claims paired procedure codes outpatient claims. used Cox regression estimate hazards ratios (HR) without SRE, compared metastasis.Among 126,123 a median follow-up 0.6 years, 24,820 (19.8%) had either at diagnosis (9,523, 7.6%) during (15,297, 12.1%). occurred in 12,665 (51%) metastasis. The HR for death was 2.4 (95% CI = 2.4-2.5) both but no SRE plus metastasis.Having metastasis, indicated by Medicare claims, associated cancer. found difference complicated SRE.