Exploring the Intersections between Triglyceride-rich Lipoproteins and Acute Coronary Syndrome: A Cross-sectional Study

• DOI: 10.4103/aam.aam_256_24
• Publication Date: 2025-03-12T05:03:52Z
• Authors: Priya Baluni; Sandesh Sadanand ...; Prasad Chandrakan...; Saurabh Ashok Suj...; Sachin Shivnitwar
• Keywords: Unstable angina; Hyperlipidemia; Cross-sectional study; Lipid Profile

Abstract Background: Within 20 years, cardiovascular disease (CVD), which is currently the main cause of death in Indian subcontinent, expected to overtake all other causes South Asia. Acute coronary syndrome (ACS), a critical form CVD, associated with multiple risk factors including hyperlipidemia. While triglyceride-rich lipoproteins (TRLs) and their remnants are well-studied traditional markers such as low-density lipoprotein (LDL-C) high-density lipoprotein-cholesterol (HDL-C), new research indicates that they may possibly be important ACS risk. Delayed removal CM very LDL has been linked increased This study aims explore association between TRL-C, surrogate marker for these atherogenic lipoproteins, ACS. Materials Methods: Between November 2018 March 2020, cross-sectional was carried out hospitals at Smt. Sucheta Kriplani Hospital Lady Hardinge Medical College New Delhi. The included 200 patients aged 18 or older, diagnosed Data were collected on lipid profiles cardiac biomarkers from venous blood samples. TRL-C computed by subtracting LDL-C HDL-C total cholesterol. Patients divided into three groups according type had ST elevation myocardial infarction (STEMI), non-ST (NSTEMI), unstable angina (UA). Statistical analyses, ANOVA Kruskal–Wallis tests, used examine associations levels types. Results: average significantly higher STEMI (43.68 mg/dL) compared NSTEMI (31.27 UA (25.31 (P < 0.0001). found no significant use statins previous events spectrum current Conclusion: severity ACS, correlating more severe forms condition. Despite statins, remained predictor severity, suggesting could valuable assessing beyond profiles. Further needed role recurrent its potential utility refining treatment strategies.