Bone Mineral Density in Chronic Liver Disease Patients: High Prevalence of Osteopenia and Osteoporosis in Patients of Advanced Cirrhosis

• DOI: 10.4103/ajim.ajim_3_24
• Publication Date: 2025-05-12T10:00:29Z
• Authors: Rakesh Kumar Koul; Anees Ahmad Nengroo; Nisar Ahmad Shah; Shagufta Parveen; Sabhiya Majeed; Qudsia Fatima
• Keywords: Osteopenia; Chronic liver disease; Liver disease; Bone disease

Abstract Background: Hepatic osteodystrophy is a well-known metabolic bone complication in individuals with chronic liver disease (CLD). The pathophysiology unknown, and evidence of increased risk osteoporosis osteopenia CLD inconsistent. Objective: present study aims to describe the mineral density patients explore its association severity disease. Materials Methods: Sixty confirmed cirrhosis were enrolled this study. All underwent laboratory measurements densitometry (BMD) using dual X-ray absorptiometry. Results: Low BMD was found 43 (71.66%) patients, only 17 (28.33%) had normal BMD. causes hepatitis B 12 (20%) C 11 (18.33%), cryptogenic 37 (61.66%) patients. Out 26 (43.33%) osteoporosis. A statistically significant difference between low marrow terms calcium bilirubin levels. serum high levels as compared those Bone worsens worsening (Child [ n = 14/14, 100%], Child 17/19, 89%], 12/27, 45%]). Conclusion: showed that highly prevalent variable etiologies. progresses directly correlates Child–Turcotte–Pugh (CTP) score. Due prevalence, these should undergo routine assessment if required, be treated for before their CTP score worsens.