Primary pulmonary extraskeletal Ewing sarcoma/Primitive neuroectodermal tumor: Two case reports

• DOI: 10.4103/ejb.ejb_48_16
• Publication Date: 2017-04-25T10:38:38Z
• Authors: Eman Sobh; Wael H. El-Sheshtawy; Shady E. Anis
• Keywords: Histopathology; Primitive neuroectodermal tumor; Presentation (obstetrics)

Primary pulmonary extraskeletal Ewing sarcoma (EES)/ primitive neuroectodermal tumor is an extremely rare with only few cases reported in the literature. In this study, we present two of primary EES diagnosed and treated at our institution. The median age was 20 years (range: 19–21). Cough, dyspnea, hemoptysis were predominant features presentation, associated a large lung mass on imaging. Image-guided core needle biopsies diagnostic modalities for both patients. Initial histopathology showed malignant small round cell tumor, which has been confirmed by immunohistochemistry as EES. Both patients received neoadjuvant chemotherapy followed surgery; postoperative pathology first patient 98% necrosis, whereas second patient’s no evidence residual after complete surgical excision.