Rhabdomyolysis-Induced Acute Kidney Injury Treated with Medium Cut-Off Membrane: A Case Report

• DOI: 10.4103/ijn.ijn_151_22
• Publication Date: 2023-11-08T09:06:29Z
• Authors: Girish V. Kumthekar; Urvi Shukla; Veena Purandare
• Keywords: Myoglobinuria; Creatine kinase; Azotemia; Dialysis tubing

Abstract Acute kidney injury can complicate rhabdomyolysis in 10-40% patients. Myoglobinuria and elevated creatine kinase (CK) form the basis of diagnosis. When associated with azotemia and/or oliguria, intermittent hemodialysis is a treatment option. 31-year-old young man came lower limb pain after doing 800 sit ups. At presentation, blood pressure was high, serum creatinine 15.7mg/dl kinase(CK)>20000 IU/L. Intermittent dialysis initiated. He developed posterior reversible encephalopathy syndrome, generalized tonic clonic convulsions further rise CK. underwent extracorporeal removal myoglobin medium cut-off (MCO) membrane. After 3 sessions MCO membrane, CK levels reduced. transitioned to conventional discharged stable condition complete renal recovery. Medium membrane effectively removes circulating without significant albumin loss cost effective.