Comparison of macular pigment optical density in patients with dry and wet age-related macular degeneration

• DOI: 10.4103/ijo.ijo_365_16
• Publication Date: 2017-06-22T12:41:37Z
• Authors: Mahmut Kaya; Ayhan Ozyurt; Nilufer Kocak; Pınar Akan; OzlemGursoy Calan; Taylan Ozturk; Eyup Karahan; Suleyman Kaynak
• Keywords: Optical density

Aim: The aim of the study was to evaluate macular pigment optical density (MPOD) levels in patients with wet age-related degeneration (AMD), dry AMD, and also healthy controls. Settings Design: This conducted at Department Ophthalmology, design a prospective study. Patients Methods: Forty-eight 51 50 controls were included All naive both previous lutein or zeaxanthin administration any intravitreal injections. Fundus reflectance (VISUCAM 500, single 460 nm wavelength) used measure MPOD levels. Three groups compared regarding age, gender, serum lutein, concentrations as well Results: Serum significantly higher control group when AMD (Group 1) 2) (P = 0.001 P < 0.001, respectively). Mean found be similar all three subgroups 0.630). However, maximum Group 1 2 0.003). There no correlation between mean 0.815, r 0.014 0.461, 0.043, respectively), but there weak concentration level 0.042, 0.124). Maximum correlated 1, 2, 3; 0.184, 0.041). Conclusion: lower cases. Groups. These results can applied clinically keeping mind that measurements one wavelength reflectometry may not completely reliable.