Fungal infection in post-renal transplant patient: Single-center experience

• DOI: 10.4103/ijpm.ijpm_306_19
• Publication Date: 2020-10-27T16:47:34Z
• Authors: KrishanL Gupta; Sahil Bagai; Raja Ramachandran; Vivek Kumar; Manish Rathi; HarbirS Kohli; Ashish Sharma; Arunaloke Chakrab...
• Keywords: Etiology

<br><b>Introduction:</b> Fungi are ubiquitous organisms and significantly alter the post-transplant course. They a major cause of morbidity mortality more so in developing countries. <b>Aims:</b> To study clinical profile, etiology, risk factors, treatment, outcome fungal infections post-renal transplant recipients. <b>Materials Methods:</b> This was cross-sectional observational retrospective from January 2014 to June 2017 wherein renal recipients with invasive infection were included followed. <b>Results:</b> Amongst 550 recipients, 56 (10.2%) patients developed infection. Mean age 40.61 ± 10.06 (13-66) years mean duration acquiring 25.33 23.65 (1-96) months. Male female ratio 3:1. Fever commonest presentation observed 89.3% patients. Cough (76.8%), breathlessness (64.3%), sputum (55.3%), hypoxia (50%), hemoptysis (10.7%) other common symptoms at presentation. serum creatinine 1.70 mg/dl. Most isolated Mucormycosis 15 (26.7%), foolwed by Aspergillosis 13 (23.2%), Pneumocystis jiroveci 12 (21.4%), Cryptococcus 6 (10.7%), Candida 4 (7.1%), Histoplasmosis 3 (5.3%), Phaeohypomycosis 2 (3.5%), 5 (8.9%) had undetermined etiology. Twenty (35.7%) evidence dual Use antithymocyte globulin 27 (48.2%), diabetes mellitus 18 (32.1%), Cytomegalovirus (CMV) 16 (28.5%), anti-rejection therapy 9 (16%), Hepatitis C 7 (12.5%) some identified factors. Ten (17.8%) graft loss (21.4%) died period. <b>Conclusions:</b> Invasive is serious threat Patient survival affected world.<br>