Severe Aortic Stenosis: Reverse Cardiac Remodeling after Surgical Aortic Valve Replacement

• DOI: 10.4103/jcecho.jcecho_76_24
• Publication Date: 2025-05-01T06:53:06Z
• Authors: Carla Rafaela de ...; Joana Amaral Lopes; Rodrigo Silva; Filipe Silva Vilela; Cátia Costa Oliveira; Fernando Mané

Context: Aortic stenosis (AS) induces ventricular remodeling. After surgical aortic valve replacement (SAVR), there is reverse remodeling (RR) that might impact patients’ prognosis. Aims: This study aims to characterize cardiac RR post-SAVR, determine possible explanatory factors of this phenomenon, and assess its prognostic impact. Methods: A retrospective observational 114 patients with severe AS who underwent SAVR between 2017 2021 had echocardiographic follow-up 1 year after. descriptive analysis baseline characteristics the was carried out, pre- post-surgical comparisons. Factors associated left (LVRR) time occurrence a major adverse event (MACE) were assessed. Results: total included, median age 72 years. One-year post-SAVR ventricle mass index (LVMi) decreased 16.9% ( P < 0.01), functional class improved (patients in New York Heart Association (NYHA) I 57, 9% vs. NYHA pre-SAVR 11, 4%; 0.01) electrocardiographic criteria for hypertrophy less common (19% 43% pre-SAVR, 0.01). Basal LVMi only independent predictor 1-year (B = 0.51 IC95% (0.34–0.68); In multivariate analysis, MACE, hazard ratio 1.11 0.026). Conclusions: Results suggest LVRR basal phenomenon. Age identified risk factor while no association found latest LVRR.