Epidemiological characteristics of Klebsiella ozaenae infection and its antibiotic susceptibility: Experience of a tertiary care hospital in the Eastern Province of Saudi Arabia

• DOI: 10.4103/jfcm.jfcm_280_23
• Publication Date: 2024-04-15T15:00:43Z
• Authors: Reem AlJindan
• Keywords: Tertiary care; Klebsiella

BACKGROUND: Klebsiella ozaenae ( K . ), a forgotten pathogen that normally colonizes the upper respiratory mucosa, can be associated with severe and invasive infections. The objectives of this study were to determine frequency isolation at microbiology laboratory in tertiary hospital scope diseases it characterize its antimicrobial susceptibility pattern. MATERIALS AND METHODS: This cross-sectional analyzed retrospective data, from 2002 2021, on cases laboratory-confirmed care hospital. primary outcome was identify infections their patterns. done by cultivation microbiological culture media, whereas identification pattern performed using either Microscan or Vitek automated systems. Data gathered Excel. percentage resistance calculated as number resistant isolates total multiplied 100. Similarly, sensitivity sensitive RESULTS: detected 59 during period. urinary tract (39%), nasal (18.6%), other including sinusitis, bronchiectasis, pneumonia (16.9%), wound (15.3%). It also such bacteremia (3.4%) abscesses (3.4%). showed multiple antibiotic classes, but ampicillin, piperacillin, nalidixic acid, nitrofurantoin. had higher than infections, particularly amoxicillin/clavulanic acid P = 0.007, 95% confidence interval [CI]: 1.84–375), ciprofloxacin < 0.0001, CI: 4.6–111.2), trimethoprim/sulfamethoxazole 0.001, 3.1–63.6). CONCLUSION: Our data show is spectrum wider expected unique