The Relationship of Clusterin Expression with Ki-67 Expression and Clinicopathological Factors in Human Renal Cell Carcinoma

• DOI: 10.4111/kju.2007.48.3.244
• Publication Date: 2009-10-30T16:15:03Z
• Authors: Hyun Cheol Park; Jeong Man Kim; Chang Leol Lee; Wan Lee; Sang Don Lee; Jeong Zoo Lee; Moon Kee Chung
• Keywords: Clusterin; Nephrology

Purpose: This study was performed to evaluate the relationship of expressions clusterin with Ki-67 and clinicopathological factors significance expression in human renal cell carcinoma (RCC). Materials Methods: Normal kidney (n=26) RCC tissues (n=111) were obtained from 111 patients who had undergone a radical or partial nephrectomy. The protein analysed using immunohistochemical staining. medical records retrospectively reviewed factors. Results: In contrast 30.8 11.5%, respectively normal (n=26), those 93.7 28.8% (n=111), (p 0.05). Furthermore, recurrence-free survival strong significantly lower than weak (p<0.05). Conclusions: These findings suggest that may be involved progression and; therefore, useful prognostic variable an RCC. (Korean J Urol 2007;48:244-251)