Peste des petits ruminants virus infection induces endoplasmic reticulum stress and apoptosis via IRE1-XBP1 and IRE1-JNK signaling pathways

• DOI: 10.4142/jvs.23236
• Publication Date: 2024-02-22T06:10:13Z
• Authors: Shuyi Yuan; Yanfen Liu; Yun Mu; Yongshen Kuang; Shaohong Chen; Yun-Tao Zhao; You Liu
• Keywords: XBP1; Protein kinase R

Peste des petits ruminants (PPR) is a contagious and fatal disease of sheep goats. PPR virus (PPRV) infection induces endoplasmic reticulum (ER) stress-mediated unfolded protein response (UPR). The activation UPR signaling pathways their impact on apoptosis replication remains controversial.