Cytotoxic T lymphocytes: Sniping cancer stem cells

• DOI: 10.4161/onci.1.1.18075
• Publication Date: 2012-01-02T15:09:00Z
• Authors: Yoshihiko Hirohashi; Toshihiko Torigoe; Satoko Inoda; Rena Morita; Vitaly Kochin; Noriyuki Sato
• Keywords: 03 medical and health sciences; 0302 clinical medicine; Author's View; 3. Good health

Cancer stem cells (CSCs)/cancer-initiating (CICs) are characterized as a small population of cancer that have high tumor-initiating ability. CSCs/CICs resistant to several therapies, and eradication is essential cure cancer. How can we eradicate CSCs/CICs? Cytotoxic T lymphocytes (CTLs) might be promising answer.