Improvement of andropause symptoms by dandelion and rooibos extract complex CRS-10 in aging male

• DOI: 10.4162/nrp.2012.6.6.505
• Publication Date: 2013-01-09T03:48:22Z
• Authors: Yoo-Hun Noh; Do-Hee Kim; Joon Yub Kim; Jiae Park; Ok Hyeon Kim; Daeseok Han; Won-Yong Kim; Sung-Su Kim; Moo-Yeol Lee; Seok-Hyun Heo; Misook Kim; Won Bok Lee; Yoonhwa Jeong; Soon Chul Myung
• Keywords: 0303 health sciences; 03 medical and health sciences; Original Research

Many aging male suffer various andropause symptoms including loss of physical and mental activities. This study evaluated the putative alleviative effects CRS-10 dandelion rooibos extract complex (CRS-10) on andropause. The survival rate TM3 Leydig cells (TM3 cells) treated with was measured based typical physiological stress. After daily intake for 4 weeks, level testosterone, activity both number sperm in older rats (18 weeks) were measured. Furthermore, thirty males surveyed AMS (Aging Males' Symptoms) questionnaire after 400 mg CRS-10. Overall, protected from serum restriction oxidative stress via activation ERK Akt pathways. testosterone spermatogenesis significantly enhanced. In addition, locomotion markedly improved. Daily improved quality life among agingmale respondents, according to a clinical survey using AMS. results indicate potential as safe efficacious natural substance reducing or alleviating symptoms.