Dietary isoflavone intake among breast cancer survivors and cancer-free women

• DOI: 10.4162/nrp.2025.19.1.80
• Publication Date: 2025-02-06T06:20:02Z
• Authors: Sihan Song; Hyeong-Gon Moon; Dong-Young Noh; So-Youn Jung; Eun Sook Lee; Zisun Kim; Hyun Jo Youn; Jihyoung Cho; Young Bum Yoo; Se Kyung Lee; Jeong Eon Lee; Seok Jin Nam; Yoo Seok Kim; Jun Won Min; Shinyoung Jun; Hyojee Joung; Jung Eun Lee
• Keywords: Soy Isoflavones

Isoflavones are estrogen-like compounds found in plants and their health effects remain equivocal. We investigated dietary isoflavone intake its associated factors Korean breast cancer survivors, with a comparison to cancer-free women. The usual of survivors (n = 981, mean age 52 yrs) 9 hospitals between 2012 2019 was assessed using 3-day food records or frequency questionnaires (FFQs). They were age-matched 2,943 women who completed FFQs as part nationwide study conducted 2016. used the flavonoid database common foods Phenol-Explorer estimate intake. contribution each group total calculated. adjusted least-squares means according lifestyle clinical calculated generalized linear models. Breast had higher (23.59 mg/day) than (17.81 mg/day). Major sources, including tofu, soybeans, doenjang, contributed over 70% both groups. When we estimated characteristics, increased scores adherence American Cancer Society guidelines but decreased increasing body mass index Among women, among those never smoked supplement users. intakes did not vary time since surgery estrogen receptor status. more likely consume isoflavones Dietary healthy characteristics without cancer. Further research is needed understand role compared on prognosis.