Vancomycin-Associated Spontaneous Cutaneous Adverse Drug Reactions

• DOI: 10.4168/aair.2011.3.3.194
• Publication Date: 2011-06-21T08:20:52Z
• Authors: So-Yeon An; Eui-Kyung Hwang; Joo-Hee Kim; Jeong-Eun Kim; Hyun-Jung Jin; Sun-Min Jin; Jin-Ok Kyun; Young-Hee Lee; Hae-Sim Park; Young Wha Choi; Seung-Kwan Lim; Young-Min Ye
• Keywords: Ototoxicity; Drug eruption; Drug reaction; Adverse drug reaction; Nephrotoxicity; Drug allergy

vasculitis, anaphylaxis, 4 ototoxicity, neutropenia, fixed drug eruptions, fever, phlebitis, nephrotoxicity, 5 thrombocytopenia, 6 and, more rarely, Stevens-Johnson or rash with eosinophilia and systemic symptoms (DRESS) syndrome have been reported. 7A recent study conducted at six Korean pharmacovigilance centers (PVCs) reported that antibiotics including vancomycin were the most prevalent causes of ADRs, skin manifestations common in spontaneously ADRs. 8Of 1,418 cases study, 3.1% associated vancomycin.