Diagnostic and prognostic impact of fluorodeoxyglucose-positron emission tomography in diagnosing intraductal papillary neoplasms of the bile duct of the liver

• DOI: 10.4174/astr.2022.102.6.335
• Publication Date: 2022-06-17T05:05:07Z
• Authors: Jin Uk Choi; Shin Hwang; Chul-Soo Ahn; Deok-Bog Moon; Tae-Yong Ha; Gi-Won Song; Dong-Hwan Jung; Jae Seung Kim; Seung-Mo Hong
• Keywords: Fluorodeoxyglucose

Malignant intraductal papillary neoplasm of the bile duct liver (IPNB-L) cannot readily be diagnosed through preoperative CT or MRI, but fluorodeoxyglucose (FDG)-PET is a viable alternative. This study evaluated diagnostic and prognostic impacts FDG-PET in patients with IPNB-L.This was retrospective single-center 101 IPNB-L who underwent hepatectomy between 2010 2019.Mean age 64.4 ± 8.3 years 76 (75.2%) were male. Anatomical hepatic resection performed 99 (98.0%). Concurrent pancreaticoduodenectomy 41 (40.6%) 1 (1.0%), respectively. R0 R1 resections 88 (87.1%) 13 (12.9%), Low-grade intraepithelial neoplasia high-grade neoplasia/invasive carcinoma 19 (18.8%) 82 (81.2%), Median maximal standardized uptake values (SUVmax) low-grade neoplasia/carcinoma 3.6 (range, 1.7-7.6) 5.2 1.5-18.7) (P = 0.019), Receiver operating characteristic curve analysis SUVmax showed area under 0.674, sensitivity 84.2% specificity 47.4% at cutoff 3.0. had no significant influence on tumor recurrence 0.832) patient survival 0.996) invasive carcinoma.IPNB-L rare type biliary encompasses histological spectrum ranging from benign disease to carcinoma. An 3.0 appears effectively discern neoplasia, which will assist surgical strategy for these cases.